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DHODH-IN-1

DHODH-IN-1

Item no.	HY-135282-1ea
Manufacturer	MedChem Express
CASRN	1800296-63-2
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.92
Citations	[1]Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.
Smiles	FC1=CC(C2CC2)=CN=C1N3N=C(OC(C)C)C(OC4=C(F)C=CC=C4F)=C3C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	403.40
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Manufacturers Target	Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Manufacturers Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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