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BAY 2476568

BAY 2476568

Item no.	HY-134877-1ea
Manufacturer	MedChem Express
CASRN	2311901-93-4
Amount	1ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.05
Citations	[1]Stephan Siegel, et al. 4h-pyrrolo[3,2-c]pyridin-4-one derivatives. WO2019081486A1.
Smiles	O=C1C2=C(NC(C3=C(OCC(C)(OC)C)C=NC=C3)=C2NC4=CC=CC(F)=C4OC)CCN1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	BAY 2476568 is a potent and selective EGFR inhibitor, with IC50s of < 0.2 nM for wild-type EGFR and several mutations (EGFRR ex20insSVD, EGFRR ex20insASV, EGFRR ex20insNPG)[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	454.49
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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