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NRP1 antagonist 1

NRP1 antagonist 1

Item no.	HY-133034-25mg
Manufacturer	MedChem Express
CASRN	2569598-01-0
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.80
Formula	C22H22N6OS2
Citations	[1]Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28(1):115183.
Smiles	O=C(NC1=NN=C(CC)S1)CSC2=NN=C(C3=CC=C(C)C=C3)N2C4=CC=CC(C)=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	450.58
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Complement System
Manufacturers Target	Complement System
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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