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Thalidomide-NH-PEG2-C2-NH-Boc

Thalidomide-NH-PEG2-C2-NH-Boc

Item no.	HY-130853-100mg
Manufacturer	MedChem Express
CASRN	2097509-40-3
Amount	100 mg
Quantity options	100 mg 10mM*1 mL 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.37
Formula	C24H32N4O8
Citations	[1]David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.
Smiles	O=C(OC(C)(C)C)NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2097509-40-3
Similar products	2097509-40-3
Available
Product Description	Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].
StorageTemperature	-20°C (Powder, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	504.53
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL
Target	Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Manufacturers Target	Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Isoform	Cereblon
Manufacturers Pathway	Apoptosis; Autophagy; PROTAC
Manufacturers Product type	Reference compound

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