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GSK-3β inhibitor 2

GSK-3β inhibitor 2

Item no.	HY-130795-10mM
Manufacturer	MedChem Express
CASRN	1702428-31-6
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	96.63
Formula	C14H14N4O3S
Citations	[1]Sivaprakasam P, et al. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg Med Chem Lett. 2015 May 1;25(9):1856-63.
Smiles	O=C(C1=C(OC)N=C(C2=CC(NC(C3CC3)=O)=NC=C2)S1)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1702428-31-6
Similar products	1702428-31-6
Available
Product Description	GSK-3β inhibitor 2 (Compound 3) is a potent, selective and orally active GSK-3β inhibitor with an IC50 of 1.1 nM. GSK-3β inhibitor 2 can cross the blood-brain barrier. GSK-3β inhibitor 2 has the potential for Alzheimer's disease[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	318.35
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 5 mg/mL (ultrasonic)
Target	GSK-3
Manufacturers Target	GSK-3
Isoform	GSK-3β
Manufacturers Pathway	PI3K/Akt/mTOR; Stem Cell/Wnt
Manufacturers Product type	Reference compound

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