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MDM2-IN-1

MDM2-IN-1

Item no.	HY-130684-5mg
Manufacturer	MedChem Express
CASRN	1410737-09-5
Amount	5 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.06
Formula	C23H21Cl2FN2O3
Citations	[1]Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57(24):10486-98.
Smiles	O=C([C@H](N1)[C@H](C2=CC=CC(Cl)=C2F)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1410737-09-5
Similar products	1410737-09-5
Available
Product Description	MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	463.33
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMF : 10 mg/mL (ultrasonic; warming; heat to 60°C)\|DMSO : 22 mg/mL (ultrasonic; warming; heat to 80°C)
Target	MDM-2/p53
Manufacturers Target	MDM-2/p53
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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