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Boc-C1-PEG3-C4-OBn

Boc-C1-PEG3-C4-OBn

Item no.	HY-130619-25mg
Manufacturer	MedChem Express
CASRN	2381196-81-0
Amount	25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	95.77
Formula	C23H38O6
Citations	[1]Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTACDegrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
Smiles	O=C(OC(C)(C)C)COCCOCCOCCCCCCOCC1=CC=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1 (HY-125878). PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	410.54
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	PROTAC Linkers
Isoform	Alkyl/ether Linkers; PEG Linkers
Pathway	PROTAC
Manufacturers Product type	Reference compound

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