Comparison

Nampt-IN-5 European Partner

Item no. HY-130606-100mg
Manufacturer MedChem Express
CASRN 2380013-17-0
Amount 100 mg
Quantity options 100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.02
Formula C25H25N5O2
Citations [1]Palacios DS, et al. Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT).ACS Med Chem Lett. 2019 Oct 10;10(11):1524-1529.
Smiles O=C(N1CC(C2=CC=CN=C2)C1)NC3=CC=C(CN4C5=CC=CC=C5N=C4OCC)C=C3
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 2380013-17-0
Similar products 2380013-17-0
Available
Product Description
Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 also inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively[1].
StorageTemperature
-20°C, 3 years (Powder)
Shipping
Blue Ice
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
427.50
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
DMSO : 50 mg/mL (ultrasonic)
Target
Cytochrome P450; NAMPT
Manufacturers Target
Cytochrome P450; NAMPT
Isoform
CYP3
Manufacturers Pathway
Metabolic Enzyme/Protease
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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