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Maleimido-tri(ethylene glycol)-propionic acid

Maleimido-tri(ethylene glycol)-propionic acid

Item no.	HY-130426-250mg
Manufacturer	MedChem Express
CASRN	518044-40-1
Amount	250 mg
Quantity options	100 mg 250 mg 25 mg 50 mg
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Food Additives Preservatives
Type	Inhibitors
Specific against	other
Purity	99.14
Formula	C13H19NO7
Citations	[1]Zhou D,et al. Novel PIKK inhibitor antibody-drug conjugates: Synthesis and anti-tumor activity.Bioorg Med Chem Lett. 2019 Apr 1;29(7):943-947.
Smiles	O=C(O)CCOCCOCCOCCN1C(C=CC1=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Mal-PEG3-acid
Similar products	518044-40-1
Shipping condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	ADC Linker; PROTAC Linkers
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	301.29
Product Description	Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Isoform	Cleavable Linker; PEG Linkers
Clinical information	No Development Reported

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HY-130426-250mg-safety-datasheet.pdf