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Maleimido-tri(ethylene glycol)-propionic acid

Maleimido-tri(ethylene glycol)-propionic acid

Item no.	HY-130426-100mg
Manufacturer	MedChem Express
CASRN	518044-40-1
Amount	100 mg
Quantity options	100 mg 250 mg 25 mg 50 mg
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Food Additives Preservatives
Type	Inhibitors
Specific against	other
Purity	99.14
Formula	C13H19NO7
Citations	[1]Zhou D,et al. Novel PIKK inhibitor antibody-drug conjugates: Synthesis and anti-tumor activity.Bioorg Med Chem Lett. 2019 Apr 1;29(7):943-947.
Smiles	O=C(O)CCOCCOCCOCCN1C(C=CC1=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Mal-PEG3-acid
Similar products	518044-40-1
Available
Product Description	Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	301.29
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Cleavable Linker; PEG Linkers
Pathway	Antibody-drug Conjugate/ADC Related; PROTAC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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