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Propargyl-PEG7-NHS ester

Propargyl-PEG7-NHS ester

Item no.	HY-130381-1ea
Manufacturer	MedChem Express
CASRN	2093152-77-1
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C22H35NO11
Citations	[1]Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.
Smiles	C#CCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	489.51
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type	ADC Related

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