EACC

Item no.	HY-129111-100mg
Manufacturer	MedChem Express
CASRN	864941-31-1
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.72
Formula	C13H11N3O6S2
Citations	[1]Vats S, et al. A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. Mol Biol Cell. 2019 Aug 1;30(17):2283-2295.
Smiles	O=C(OCC)NC(C1=C(NC(C2=CC=C([N+]([O-])=O)S2)=O)SC=C1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	864941-31-1
Available
Product Description	EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	369.37
Clinical Information	No Development Reported
Manufacturers Research Area	Infection; Neurological Disease
Solubility	DMSO : 16.88 mg/mL (ultrasonic)
Target	Autophagy
Manufacturers Target	Autophagy
Manufacturers Pathway	Autophagy
Manufacturers Product type	Reference compound

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HY-129111-100mg-safety-datasheet.pdf