EC0488

Item no.	HY-128939-1ea
Manufacturer	MedChem Express
CASRN	1059477-92-7
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C65H98N16O34S
Citations	[1]Leamon CP, et al. Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy. Cancer Chemother Pharmacol. 2017 Jun;79(6):1151-1160.
Smiles	O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	1679.63
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Antifolate
Pathway	Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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