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HDAC-IN-4

HDAC-IN-4

Item no.	HY-128763-10mM
Manufacturer	MedChem Express
CASRN	1252003-13-6
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.82
Formula	C20H21N3O2
Citations	[1]Géraldy M, et al. Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated. J Med Chem. 2019 May 9;62(9):4426-4443.
Smiles	O=C(NO)C1=CC=C(CN2C(CN(C)CC3)=C3C4=C2C=CC=C4)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	335.40
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	HDAC
Pathway	Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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