« Back
Home /
BMS-986115

BMS-986115

Item no.	HY-12860-10mg
Manufacturer	MedChem Express
CASRN	1584647-27-7
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.81
Formula	C26H25F7N4O3
Citations	[1]Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1.
Smiles	O=C(N[C@@H]1C(NC2=C(C)C=CC=C2C(C3=CC=CC(F)=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Notch inhibitor 1
Available
Product Description	BMS-986115 (Notch inhibitor 1) is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	574.49
Clinical_Information	Phase 1
Manufacturers Research_Area	Cancer
Solubility	DMSO : 13.12 mg/mL (ultrasonic; warming; heat to 70°C)
Manufacturers Target	Notch
Pathway	Neuronal Signaling; Stem Cell/Wnt
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10 mg

available

Request delivery time