PQM130

Item no.	HY-128346-1ea
Manufacturer	MedChem Express
CASRN	2089415-51-8
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.17
Citations	[1]Morroni F, et al. PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease. Front Pharmacol. 2019 Jun 12;10:658.
Smiles	O=C(OCC1CCN(CC2=CC=CC=C2)CC1)/C=C/C3=CC=C(O)C(OC)=C3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	PQM130, a Feruloyl-Donepezil Hybrid compound with brain penatration, is a multitarget agent candidate against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity. PQM130 acts as a neuroprotective compound for anti-AD agent development[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	381.46
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 1.82 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Amyloid-β
Manufacturers Target	Amyloid-β
Manufacturers Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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