Comparison

R(+)-Methylindazone European Partner

Item no. HY-12693-5mg
Manufacturer MedChem Express
CASRN 54197-31-8
Amount 5 mg
Quantity options 10mM/1mL 10 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.17
Formula C17H18Cl2O4
Citations [1]Landry DW, et al. Epithelial chloride channel. Development of inhibitory ligands. J Gen Physiol. 1987 Dec;90(6):779-98.<br/>[2]Landry DW, et al. Purification and reconstitution of chloride channels from kidney and trachea. Science. 1989 Jun 23;244(4911):1469-72.<br/>[3]Xiaoqin Fan, et al. A homogeneous time-resolved fluorescence-based high-throughput screening for discovery of inhibitors of Nef-sdAb19 interaction. Int J Oncol. 2015 Oct;47(4):1485-93.
Smiles O=C(O)COC1=CC2=C(C([C@@](C)(C3CCCC3)C2)=O)C(Cl)=C1Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias R(+)-IAA-94
Available
Product Description
R(+)-Methylindazone (R(+)-IAA-94) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-Methylindazone inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef)[1][2][3].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
MolecularWeight
357.23
Clinical Information
No Development Reported
Manufacturers Research Area
Others
Solubility
DMSO : ≥ 100 mg/mL|H2O : 0.1 mg/mL (ultrasonic)
Target
Chloride Channel
Manufacturers Target
Chloride Channel
Manufacturers Pathway
Membrane Transporter/Ion Channel
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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