Comparison

D-Luciferin (sodium) European Partner

Item no. HY-12591-5mg
Manufacturer MedChem Express
CASRN 103404-75-7
Amount 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.92
Formula C11H7N2NaO3S2
Citations Adv Funct Mater. 2023 Sep 15.<br>Cell Mol Gastroenterol Hepatol. 2021;12(3):839-856.<br>J Leukoc Biol. 2019 Nov;106(5):1089-1100. <br>Sci China Life Sci. 2021 May 27;1-21.<br>Vet Res. 2021 Jun 26;52(1):95.<br>Acta Pharm Sin B. 12 March 2022.<br>Autophagy. 2023 Sep 21.<br>Biomed Pharmacother. 2019 Sep;117:109126.<br>bioRxiv. 2023 Apr 10.<br>BMC Cancer. 2023 Oct 31;23(1):1047.<br>Cancer Lett. 2023 Sep 21;216403.<br>Cell Chem Biol. 2021 Nov 23;S2451-9456(21)00482-7.<br>Cell Death Dis. 2020 Sep 17;11(9):765.<br>Compos Part B-Eng. 2024 Feb 15, 271, 111162.<br>Hortic Res. 2022 Jan 20;uhab088.<br>New Phytol. 2022 Sep 2.<br>Parasit Vectors. 2023 Apr 24;16(1):139.<br>Plant Cell Environ. 2023 Mar 9.<br>Plant Physiol. 2021 Jun 11;186(2):1302-1317.<br>Research Square Print. December 19th, 2022.<br>SSRN. 2023 Sep 15.<br>Acta Pharm Sin B. 2023 Sep 1.<br>Acta Pharmacol Sin. 2021 Jul 29.<br>Asian J Pharm Sci. 10 June 2022.<br>Autophagy. 2022 Nov 30.<br>Cell Metab. 2022 Sep 7;S1550-4131(22)00359-X.<br>Gastro Hep Adv. 2022.<br>Int J Oncol. 2020 Mar;56(3):761-771.<br>J Nanobiotechnology. 2023 Oct 19;21(1):383.<br>Mil Med Res. 2023 Jul 25;10(1):34.<br>New Phytol. 2023 Jun 15.<br>Pharmacol Res. 2021 Apr;166:105527.<br>Plant Cell Environ. 2023 Feb 9.<br>Plant Physiol. 2023 Aug 11;kiad452.<br>Research Square Print. 2023 Feb 3.<br>SSRN. 2023 Mar 20.<br>[1]Giuseppe Meroni, et al. D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity. ARKIVOC 2009 (i) 265-288.<br>[2]Inoue Y, et al. Timing of imaging after d-luciferin injection affects the longitudinal assessment of tumor growthusing in vivo bioluminescence imaging. Int J Biomed Imaging. 2010;2010:471408.<br>[3]Rajesh Shinde, et al. Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays. Biochemistry. 2006 Sep 19;45(37):11103-12.
Smiles O=C([C@@H]1N=C(C2=NC3=CC=C(O)C=C3S2)SC1)O[Na]
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias D-(-)-Luciferin (sodium); Firefly luciferin (sodium); Beetle Luciferin (sodium)
Available
Product Description
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP[1]. We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
StorageTemperature
4°C (Powder, sealed storage, away from moisture and light)
Shipping
Room Temperature
MolecularWeight
302.30
Clinical_Information
No Development Reported
Manufacturers Research_Area
Others
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 250 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target
Fluorescent Dye
Pathway
Others
Manufacturers Product type
Dye Reagents

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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