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DCZ3301

DCZ3301

Item no.	HY-125542-1ea
Manufacturer	MedChem Express
CASRN	2136278-38-9
Amount	1 ea
Quantity options	1 ea 1mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Xiao W, et, al. DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma. Acta Biochim Biophys Sin (Shanghai). 2018 Jul 1;50(7):643-650.
Smiles	O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=N)N=C2)=C1)NC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	DCZ3301 is a potent aryl-guanidino inhibitor. DCZ3301 inhibits cell proliferation, induces G2/M cell cycle arrest and apoptosis. DCZ3301 inhibits the activation of the PI3K/AKT pathway by downregulating the protein expression of PI3K and phosphorylation of AKT. DCZ3301 can be used in research of cancer[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	464.83
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	Akt; Apoptosis; PI3K
Manufacturers Target	Akt; Apoptosis; PI3K
Manufacturers Pathway	Apoptosis; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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