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DBCO-Sulfo-NHS ester (sodium)

DBCO-Sulfo-NHS ester (sodium)

Item no.	HY-123687-10mg
Manufacturer	MedChem Express
CASRN	1400191-52-7
Amount	10 mg
Quantity options	10 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	97.98
Formula	C25H21N2NaO8S
Citations	[1]Jung S, et al. Facile strategy for protein conjugation with chitosan-poly(ethylene glycol) hybrid microparticleplatforms via strain-promoted alkyne-azide cycloaddition (SPAAC) reaction. Biomacromolecules. 2013 Nov 11;14(11):3892-902.
Smiles	O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
StorageTemperature	-20°C (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	532.50
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	H2O : ≥ 50 mg/mL
Target	ADC Linker
Manufacturers Target	ADC Linker
Isoform	Cleavable Linker
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related
Manufacturers Product type	Dye Reagents

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