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MitoBloCK-6

MitoBloCK-6

Item no.	HY-122652-50mg
Manufacturer	MedChem Express
CASRN	303215-67-0
Amount	50 mg
Quantity options	100 mg 1 ea 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.07
Formula	C19H14Cl2N2O
Citations	[1]Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92.
Smiles	OC1=C(/C=N/C2=CC=C(NC3=CC=CC=C3)C=C2)C=C(Cl)C=C1Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	357.23
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic; warming)
Target	Apoptosis
Manufacturers Target	Apoptosis
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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