Comparison

MitoBloCK-6 European Partner

Item no. HY-122652-1ea
Manufacturer MedChem Express
CASRN 303215-67-0
Amount 1 ea
Category
Type Molecules
Specific against other
Purity 98.07
Citations [1]Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92.
Smiles OC1=C(/C=N/C2=CC=C(NC3=CC=CC=C3)C=C2)C=C(Cl)C=C1Cl
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Available
Product Description
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1].
StorageTemperature
4°C (Powder, protect from light)
Shipping
Room Temperature
Manufacturers Applications
Metabolism-protein/nucleotide metabolism
MolecularWeight
357.23
Clinical_Information
No Development Reported
Manufacturers Research_Area
Metabolic Disease
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Manufacturers Target
Apoptosis
Pathway
Apoptosis
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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