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Coronaridine

Coronaridine

Item no.	HY-121118-1ea
Manufacturer	MedChem Express
CASRN	467-77-6
Amount	1ea
Quantity options	10 mg 1ea 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.72
Citations	[1]Kensuke Ohishi, et al. Coronaridine, an iboga type alkaloid from Tabernaemontana divaricata, inhibits the Wnt signaling pathway by decreasing β-catenin mRNA expression. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3937-40.<br/>[2]Hugo R Arias, et al. Coronaridine congeners potentiate GABA A receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Jul 13;101:109930
Smiles	COC([C@]12[C@@]3([H])[N@@](CCC4=C2NC5=CC=CC=C45)C[C@@](C[C@@H]3CC)([H])C1)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Coronaridine, an iboga type alkaloid, inhibits the wnt signaling pathway by decreasing β-catenin expression[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	338.44
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Neurological Disease
Solubility	10 mM in DMSO
Target	Wnt
Manufacturers Target	Wnt
Manufacturers Pathway	Stem Cell/Wnt
Manufacturers Product type	Natural Products

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