Bizine

Item no.	HY-121095-5mg
Manufacturer	MedChem Express
CASRN	1591932-50-1
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C18H23N3O
Citations	[1]Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9(6):1284-93.
Smiles	NNCCC1=CC=C(NC(CCCC2=CC=CC=C2)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	297.39
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	Histone Demethylase
Isoform	KDM1/LSD1
Pathway	Epigenetics
Manufacturers Product type	Reference compound

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