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Zidebactam

Zidebactam

Item no.	HY-120859-1mg
Manufacturer	MedChem Express
CASRN	1436861-97-0
Amount	1 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	96.19
Formula	C13H21N5O7S
Citations	[1]Sader HS, et al. WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases. J Antimicrob Chemother. 2017 Jun 1;72(6):1696-1703.<br/>[2]Moya B, et al. WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones. Antimicrob Agents Chemother. 2017 May 24;61(6).
Smiles	O=C([C@@H]1CCCNC1)NNC([C@@H]2CC[C@@H]3C[N@]2C(N3OS(=O)(O)=O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	WCK-5107
Available
Product Description	Zidebactam (WCK-5107) is a potent β-lactamase inhibitor[1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL[2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	391.40
Clinical Information	Phase 1
Manufacturers Research Area	Infection
Solubility	DMSO : 250 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Target	Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Manufacturers Target	Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Reference compound

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