GSK205

Item no.	HY-120691A-5mg
Manufacturer	MedChem Express
CASRN	1263068-83-2
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 1mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.91
Formula	C24H25BrN4S
Citations	[1]Ye L, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 2012 Sep 28;151(1):96-110.<br>[2]Kanju P, et al. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Sci Rep. 2016 Jun 1;6:26894.
Smiles	CN(CCC1=CC=C(NC2=NC=C(C3=CC=CN=C3)S2)C=C1)CC4=CC=CC=C4.[H]Br
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1263068-83-2
Available
Product Description	GSK205 is a potent, selective TRPV4 antagonist with an IC50 of 4.19 μM for inhibiting TRPV4-mediated Ca2+ influx[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	481.45
Clinical_Information	No Development Reported
Manufacturers Research Area	Metabolic Disease; Inflammation/Immunology
Solubility	DMSO : 250 mg/mL (ultrasonic)
Manufacturers Target	TRP Channel
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling

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HY-120691A-5mg-safety-datasheet.pdf