JC124

Item no.	HY-120007-100mg
Manufacturer	MedChem Express
CASRN	1638611-48-9
Amount	100 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	97.13
Formula	C17H19ClN2O4S
Citations	[1]Ram Kuwar, et al. A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury. J Neuroinflammation. 2019 Apr 11;16(1):81.
Smiles	O=C(C1=CC(Cl)=CC=C1OC)NCCC2=CC=C(C=C2)S(=O)(NC)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	382.86
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 250 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Manufacturers Target	NOD-like Receptor (NLR)
Isoform	NLRP3
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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