Ani9

Item no.	HY-119981-10mg
Manufacturer	MedChem Express
CASRN	356102-14-2
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.53
Formula	C17H17ClN2O3
Citations	[1]Seo Y, et al. Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2. PLoS One. 2016 May 24;11(5):e0155771. <br>[2]Seo Y, et al. Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors. Eur J Med Chem. 2018 Dec 5;160:245-255.
Smiles	O=C(COC1=CC=C(C=C1C)Cl)N/N=C/C2=CC=CC=C2OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Ani9 is a potent and selective transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with IC50 at 77 nM. Ani9 can be applied to the study of cancer and other diseases[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	332.78
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Neurological Disease
Solubility	DMSO : ≥ 125 mg/mL
Manufacturers Target	Chloride Channel
Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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