AG 370

Item no.	HY-116111-1mg
Manufacturer	MedChem Express
CASRN	134036-53-6
Amount	1mg
Quantity options	100 mg 1 ea 1mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C15H9N5
Citations	[1]M C Bryckaert, et al. Inhibition of platelet-derived growth factor-induced mitogenesis and tyrosine kinase activity in cultured bone marrow fibroblasts by tyrphostins. Exp Cell Res. 1992 Apr;199(2):255-61.
Smiles	N#C/C(C#N)=C(N)/C(C#N)=C\C1=CC=C(NC=C2)C2=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	AG 370, an indole tyrphostin, is a potent PDGF-induced mitogenesis inhibotor (IC50 of 20 μM). AG 370 displays weak inhibition of the EGF receptor[1].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	259.27
Clinical Information	No Development Reported
Manufacturers Research Area	Cardiovascular Disease
Solubility	10 mM in DMSO
Target	PDGFR
Manufacturers Target	PDGFR
Isoform	PDGFR
Manufacturers Pathway	Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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