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3BrB-PP1

3BrB-PP1

Item no.	HY-115741-10mM
Manufacturer	MedChem Express
CASRN	956025-99-3
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.0
Formula	C16H18BrN5
Citations	[1]Tay YD, et, al. Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex. Cell Rep. 2019 Feb 5;26(6):1654-1667.e7.<br>[2]Mutavchiev DR, et, al. Remodeling of the Fission Yeast Cdc42 Cell-Polarity Module via the Sty1 p38 Stress-Activated Protein Kinase Pathway. Curr Biol. 2016 Nov 7;26(21):2921-2928.
Smiles	NC1=C2C(N(C(C)(C)C)N=C2CC3=CC=CC(Br)=C3)=NC=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	3BrB-PP1 is an ATP-competitive analog. 3BrB-PP1 can specifically inhibit the activity of protein kinase with mutations in the ATP-binding pocket (mutation of Thr97 within Sty1’s ATP-binding pocket)[1][2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	360.25
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mM/1mL

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