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Cytarabine triphosphate

Cytarabine triphosphate

Item no.	HY-115740-1ea
Manufacturer	MedChem Express
CASRN	13191-15-6
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C9H16N3O14P3
Citations	[1]Anderson E, et, al. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia. Exp Hematol. 2019 Jun;74:13-18.e3.
Smiles	O[C@@H]1[C@@](N2C(N=C(C=C2)N)=O)([H])O[C@@H]([C@H]1O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Ara-CTP
Available
Product Description	Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	483.16
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	DNA/RNA Synthesis
Manufacturers Target	DNA/RNA Synthesis
Manufacturers Pathway	Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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