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FRM-024

FRM-024

Item no.	HY-115726-1ea
Manufacturer	MedChem Express
CASRN	2085780-87-4
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C22H22ClN5O2
Citations	[1]Bursavich MG, et al. Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator. J Med Chem. 2021 Oct 14;64(19):14426-14447.
Smiles	CC1=CN(C2=C(OC)N=C(C3=NO[C@@H](C4CC4)[C@@H](C5=CC=C(Cl)C=C5)N3)C=C2)C=N1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	FRM-024 is a potent CNS-penetrant gamma secretase modulator for familial Alzheimer’s disease.
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	423.90
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	γ-secretase
Pathway	Neuronal Signaling; Stem Cell/Wnt
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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