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Tr-PEG2-OH

Tr-PEG2-OH

Item no.	HY-114995-1g
Manufacturer	MedChem Express
CASRN	105589-77-3
Amount	1 g
Quantity options	100 mg 10 g 1 ea 1 g 25 g 50 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.45
Formula	C23H24O3
Citations	[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.<br/>[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Smiles	OCCOCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Tr-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Tr-PEG2-OH is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	348.43
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Inflammation/Immunology
Solubility	10 mM in DMSO
Target	ADC Linker; PROTAC Linkers
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Non-cleavable Linker; PEG Linkers
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type	ADC Related

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