Item no. |
HY-114360A-100mg |
Manufacturer |
MedChem Express
|
CASRN |
38411-85-7 |
Amount |
100 mg |
Quantity options |
100 mg
1 ea
50 mg
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Formula |
C26H44NNaO6S |
Citations |
[1]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. <br/>[2]Angelico M, et al. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs. Scand J Gastroenterol. 1995 Dec;30(12):1178-85. <br/>[3]Angelico M, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. Dig Dis Sci. 1994 Nov;39(11):2389-97. <br/>[4]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. <br/>[5]Solmon Kusuma S, et al. Antineoplastic activity of monocrotaline against hepatocellular carcinoma[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 2014, 14(9): 1237-1248. |
Smiles |
C[C@@]12[C@]3([H])[C@](C[C@@H]([C@]1([H])C[C@@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)C |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Available |
|
Product Description |
Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model. |
StorageTemperature |
4°C (Powder, sealed storage, away from moisture) |
Shipping |
Room Temperature |
MolecularWeight |
521.69 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Inflammation/Immunology |
Solubility |
H2O : 62.5 mg/mL (ultrasonic) |
Target |
Interleukin Related; TNF Receptor |
Manufacturers Target |
Interleukin Related; TNF Receptor |
Isoform |
IL-6; TNFRSF1A/CD120a |
Manufacturers Pathway |
Apoptosis; Immunology/Inflammation |
Manufacturers Product type |
Biochemical Assay Reagents |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.