Comparison

(S)-Coriolic acid European Partner

Item no. HY-113884B-1ea
Manufacturer MedChem Express
CASRN 29623-28-7
Amount 1 ea
Category
Type Molecules
Specific against other
Purity 99.0
Citations [1]Yuan H, et al. 15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer. Thorax. 2010;65(4):321-326.<br>[2]Mabalirajan U, et al. Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep. 2013;3:1349.<br>[3]Ogawa E, et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. J Invest Dermatol. 2011;131(3):604-612.
Smiles CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(O)=O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias 13(S)-HODE
Available
Product Description
(S)-Coriolic acid (13(S)-HODE), the product of 15-lipoxygenase (15-LOX) metabolism of linoleic acid, functions as the endogenous ligand to activate PPARγ. (S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial injury[1][2][3].
StorageTemperature
Solution, -20°C, 2 years
Shipping
Blue Ice
Manufacturers Applications
COVID-19-anti-virus
MolecularWeight
296.44
Clinical_Information
No Development Reported
Manufacturers Research_Area
Cancer; Inflammation/Immunology
Solubility
10 mM in DMSO
Manufacturers Target
Mitochondrial Metabolism; PPAR
Pathway
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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