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2-Hydroxybutyric acid

2-Hydroxybutyric acid

Item no.	HY-113381-1ea
Manufacturer	MedChem Express
CASRN	600-15-7
Amount	1ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.0
Citations	[1]Landaas S, et al. The formation of 2-hydroxybutyric acid in experimental animals. Clin Chim Acta. 1975 Jan 6;58(1):23-32.<br>[2]Zheng N, et al., Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid. J Pharm Anal. 2020 Dec;10(6):560-570.<br>[3]Wang F, et al., Metabolomic analysis-identified 2-hydroxybutyric acid might be a key metabolite of severe preeclampsia. Open Life Sci. 2023 Feb 28;18(1):20220572.<br>[4]Shantavasinkul PC, et al., Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid. Surg Obes Relat Dis. 2018 Aug;14(8):1126-1132.
Smiles	CCC(O)C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	α-Hydroxybutyric acid
Available
Product Description	2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1]. 2-Hydroxybutyric acid is a potential biomarker for type 2 diabetes and preeclampsia[2][4]. 2-Hydroxybutyric acid prevents the acetaminophen (AP)-induced liver injury[3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	104.10
Clinical_Information	No Development Reported
Manufacturers Research_Area	Metabolic Disease; Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 50°C)
Manufacturers Target	Endogenous Metabolite
Isoform	Human Endogenous Metabolite
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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