« Back
Home /
JBSNF-000088

JBSNF-000088

Item no.	HY-112584-10mM
Manufacturer	MedChem Express
CASRN	7150-23-4
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Formula	C7H8N2O2
Citations	[1]Kannt A, et al. A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep. 2018 Feb 26;8(1):3660.
Smiles	O=C(N)C1=CC=C(OC)N=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6-Methoxynicotinamide
Available
Product Description	JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	152.15
Clinical_Information	No Development Reported
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : ≥ 100 mg/mL\|H2O : 1 mg/mL (ultrasonic)
Manufacturers Target	Others
Pathway	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-112584-10mM-safety-datasheet.pdf