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Bis-PEG2-PFP ester

Bis-PEG2-PFP ester

Item no.	HY-112560-1ea
Manufacturer	MedChem Express
CASRN	1314378-18-1
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C20H12F10O6
Citations	[1]Matthew David DOROSKI, et al. Cytotoxic peptides and antibody drug conjugates thereof. WO2013072813A2.<br/>[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Smiles	O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCC(OC2=C(F)C(F)=C(F)C(F)=C2F)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	538.29
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	ADC Linker; PROTAC Linkers
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Alkyl/ether Linkers; Non-cleavable Linker; PEG Linkers
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type	ADC Related

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