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Efflux inhibitor-1

Efflux inhibitor-1

Item no.	HY-112505-10mg
Manufacturer	MedChem Express
CASRN	1776055-29-8
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.0
Formula	C28H25N5O3
Citations	[1]Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16.
Smiles	COC1=CC=CC=C1C2=NN(C(N3CCN(C(C4=COC=C4)=O)CC3)=CC(C5=CC=CC=C5)=N6)C6=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Efflux inhibitor-1 (compound 2) is a pyrazolo[1, 5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
MolecularWeight	479.53
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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