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EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB-2/ErbB-4 inhibitor-2

Item no.	HY-112420-25mg
Manufacturer	MedChem Express
CASRN	179248-61-4
Amount	25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.69
Formula	C23H21N3O3
Citations	[1]Perry S Brignola, et al. Comparison of the biochemical and kinetic properties of the type 1 receptor tyrosine kinase intracellular domains. Demonstration of differential sensitivity to kinase inhibitors. J Biol Chem. 2002 Jan 11;277(2):1576-85.
Smiles	COC1=CC2=NC=NC(NC3=CC=C(OCC4=CC=CC=C4)C=C3)=C2C=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	EGFR/ErbB-2/ErbB-4 inhibitor-2 (Compound 5) is a EGFR and ErbB inhibitor with IC50s of 0.017 μM, 0.08 μM, 1.91 μM[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	387.43
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 33.33 mg/mL (ultrasonic)
Isoform	EGFR/ErbB1/HER1; ErbB2/HER2; ErbB4/HER4
Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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