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Pyocyanin

Pyocyanin

Item no.	HY-111278-5mg
Manufacturer	MedChem Express
CASRN	85-66-5
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.23
Formula	C13H10N2O
Citations	[1]Paulina Castañeda-Tamez, et al. Pyocyanin Restricts Social Cheating in <i>Pseudomonas aeruginosa</i>. Front Microbiol. 2018 Jun 27;9:1348.<br/>[2]Marreiro de Sales-Neto J, et al. Anti-inflammatory potential of pyocyanin in LPS-stimulated murine macrophages. Immunopharmacol Immunotoxicol. 2019 Feb;41(1):102-108.<br/>[3]Kamer AMA, et al. Antibacterial, antibiofilm, and anti-quorum sensing activities of pyocyanin against methicillin-resistant Staphylococcus aureus: in vitro and in vivo study. BMC Microbiol. 2023 Apr 24;23(1):116.<br/>[4]Arora D, et al. Pyocyanin induces systemic oxidative stress, inflammation and behavioral changes in vivo. Toxicol Mech Methods. 2018 Jul;28(6):410-414.
Smiles	O=C1C=CC=C2N(C)C3=C(N=C21)C=CC=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Pyocyanine; Sanazin; Sanasin
Available
Product Description	Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity[1][2][3][4].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	210.23
Clinical Information	No Development Reported
Manufacturers Research Area	Infection; Inflammation/Immunology
Solubility	DMSO : 9.09 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Bacterial; Drug Metabolite; Reactive Oxygen Species
Manufacturers Target	Bacterial; Drug Metabolite; Reactive Oxygen Species
Manufacturers Pathway	Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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