ML191

Item no.	HY-111083-10mg
Manufacturer	MedChem Express
CASRN	931695-79-3
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.65
Formula	C24H25N3O3
Citations	[1]Heynen-Genel S, et al. Screening for Selective Ligands for GPR55 - Antagonists. 2010 Oct 30
Smiles	O=C1OC(C2=CC=CC=C2)=NN1C3CCN(C(C4(C5=CC=C(C)C=C5)CC4)=O)CC3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CID23612552
Available
Product Description	ML-191 is an antagonist of GPR55. It inhibits GPR55 signaling induced by lysophosphatidylinositol (EC50=1.076 µM in U2OS cells overexpressing GPR55). ML-191 inhibits LPI-induced phosphorylation of ERK1/2 (IC50=328 nM) and receptor-dependent translocation of PKCβII when used at a concentration of 30 µM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	403.47
Clinical_Information	No Development Reported
Manufacturers Research_Area	Others
Solubility	DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	GPR55
Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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