« Back
Home /
Swinholide A

Swinholide A

Item no.	HY-111009-1ea
Manufacturer	MedChem Express
CASRN	95927-67-6
Amount	1 ea
Quantity options	10 mg 10 ug 1 ea 25 mg 50 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.3
Citations	[1]Inji Shin,et al. Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation. J Am Chem Soc. 2016 Nov 2;138(43):14246-14249.<br/>[2]M R Bubb, et al. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. J Biol Chem. 1995 Feb 24;270(8):3463-6.
Smiles	C[C@H]([C@](OC(/C=C/C(C)=C/C[C@@H](C[C@@](C=CC1)([H])O[C@]1([H])C[C@@H]([C@H]([C@H](C[C@H]([C@@H]2C)O)O)C)OC)O)=O)([H])[C@H]([C@@H](C[C@@H]([C@@H]([C@H](C[C@@]3([H])O[C@@](C[C@H](C/C=C(/C=C/C(O[C@]2([H])[C@@H](C)[C@@H](O)[C@@H](C)CC[C@H](O[C@H]4C)C[C@@H](C4)OC)=O)C)O)([H])C=CC3)OC)C)O)O)C)[C@@H](O)[C@@H](C)CC[C@H](O[C@H]5C)C[C@@H](C5)OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Swinholide A is the actin-binding marine polyketide and dimerizes actin with the Kd of ~ 50 nM[1]. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. Swinholide A disrupts the actin cytoskeleton of cells.Antifungal activity[2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	1389.87
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	10 mM in DMSO
Target	Fungal
Manufacturers Target	Fungal
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ea

available

Request delivery time