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Asfotase alfa

Asfotase alfa

Item no.	HY-108786-5mg
Manufacturer	MedChem Express
CASRN	1174277-80-5
Amount	5 mg
Quantity options	1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	97.88
Dry ice	Yes
Citations	[1]Yadav MC, et al. Dose response of bone-targeted enzyme replacement for murine hypophosphatasia. Bone. 2011 Aug;49(2):250-6.
Smiles	[Asfotase alfa]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ENB-0040
Available
Product Description	Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2−/− knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Clinical Information	Launched
Manufacturers Research Area	Metabolic Disease
Solubility	10 mM in DMSO
Target	Others
Manufacturers Target	Others
Manufacturers Pathway	Others
Manufacturers Product type	Inhibitory Antibodies

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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