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TM-N1324

TM-N1324

Item no.	HY-108699-25mg
Manufacturer	MedChem Express
CASRN	1144477-35-9
Amount	25 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.91
Formula	C18H13ClFN7O
Citations	[1]Frimurer TM, et al. Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions. J Med Chem. 2017 Feb 9;60(3):886-898.
Smiles	O=C1CC(C2=CC=C(F)C=C2Cl)C3=C(N(C4=C5N=CNC5=NC=N4)N=C3C)N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1144477-35-9
Available
Product Description	TM-N1324 is an agonist of G-Protein-Coupled Receptor 39 (GPR39) with EC50s of 9 nM/5 nM in the presence of Zn2+, and 280 nM/180 nM in the absence of Zn2+ for human/murine GPR39.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	397.79
Clinical_Information	No Development Reported
Manufacturers Research Area	Neurological Disease; Endocrinology
Solubility	DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	GHSR
Pathway	GPCR/G Protein

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-108699-25mg-safety-datasheet.pdf