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GPR35 agonist 4

GPR35 agonist 4

Item no.	HY-107539-5mg
Manufacturer	MedChem Express
CASRN	871085-49-3
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.0
Formula	C12H9NO5S
Citations	[1]Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.
Smiles	O=C(NC(S/1)=O)C1=C\C2=CC=C(C=C2)OCC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	279.27
Clinical_Information	No Development Reported
Manufacturers Research_Area	Others
Solubility	10 mM in DMSO
Manufacturers Target	GPR35
Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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