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MAP4343

MAP4343

Item no.	HY-107116-5mg
Manufacturer	MedChem Express
CASRN	511-26-2
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.09
Formula	C22H34O2
Citations	[1]Fontaine-Lenoir V, et, al. Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4711-6.<br/>[2]Duchossoy Y, et, al. Treatment of experimental spinal cord injury with 3β-methoxy-pregnenolone. Brain Res. 2011 Jul 27;1403:57-66.
Smiles	C[C@@]1([C@H]2C(C)=O)[C@](CC2)([H])[C@@](CC=C(C3)[C@@]4(CC[C@@H]3OC)C)([H])[C@]4([H])CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	511-26-2
Similar products	511-26-2
Available
Product Description	MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	330.50
Clinical Information	Phase 2
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)
Target	Microtubule/Tubulin
Manufacturers Target	Microtubule/Tubulin
Manufacturers Pathway	Cell Cycle/DNA Damage; Cytoskeleton
Manufacturers Product type	Reference compound

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