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Sabcomeline (hydrochloride)

Sabcomeline (hydrochloride)

Item no.	HY-106432A-10mg
Manufacturer	MedChem Express
CASRN	159912-58-0
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C10H16ClN3O
Citations	[1]Hosoi R, Kobayashi K, Ishida J, Yamaguchi M, Inoue O. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. <br/>[2]Hatcher JP, Loudon JM, Hagan JJ, Clark MS. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282.
Smiles	CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SB-202026 (hydrochloride); Memric (hydrochloride)
Available
Product Description	Sabcomeline (SB-202026) hydrochloride is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline hydrochloride can be used for Alzheimer's disease research[1][2].
StorageTemperature	4°C (Powder, stored under nitrogen, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	229.71
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	H2O : 125 mg/mL (ultrasonic)
Target	mAChR
Manufacturers Target	mAChR
Isoform	mAChR1
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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