Item no. |
HY-106359A-5mg |
Manufacturer |
MedChem Express
|
CASRN |
501019-16-5 |
Amount |
5 mg |
Quantity options |
10 mg
25 mg
50 mg
5 mg
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.55 |
Formula |
C59H105N17O11.C2H4O2 |
Citations |
[1]Arthur Kaser, et al. Novel therapeutic targets in the treatment of IBD. Kaser, Arthur; Tilg, Herbert (2008). Expert Opinion on Therapeutic Targets, 12(5), 553–563. [2]Jingsong Zhao, et al. Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity. Clin Cancer Res. 2004 Apr 15;10(8):2851-9. |
Smiles |
N=C(N)NCCC[C@@H](N)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCC)C(NCC(N[C@@H](C(N)=O)CC1=CC=C(O)C=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
RDP-58 (acetate) |
Available |
|
Product Description |
Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide acetate inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide acetate can be used for the research of ulcerative colitis[1][2]. |
StorageTemperature |
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light) |
Shipping |
Blue Ice |
Manufacturers Applications |
Cancer-programmed cell death |
MolecularWeight |
1288.62 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Cancer |
Solubility |
10 mM in DMSO |
Target |
IFNAR; Reactive Oxygen Species; TNF Receptor |
Manufacturers Target |
IFNAR; Reactive Oxygen Species; TNF Receptor |
Manufacturers Pathway |
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB |
Manufacturers Product type |
Peptides |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.