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Delmitide (acetate)

Delmitide (acetate)

Item no.	HY-106359A-25mg
Manufacturer	MedChem Express
CASRN	501019-16-5
Amount	25 mg
Quantity options	10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.55
Formula	C59H105N17O11.C2H4O2
Citations	[1]Arthur Kaser, et al. Novel therapeutic targets in the treatment of IBD. Kaser, Arthur; Tilg, Herbert (2008). Expert Opinion on Therapeutic Targets, 12(5), 553–563.<br/>[2]Jingsong Zhao, et al. Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity. Clin Cancer Res. 2004 Apr 15;10(8):2851-9.
Smiles	N=C(N)NCCC[C@@H](N)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCC)C(N[C@H](CCCC)C(N[C@H](CCCC)C(NCC(N[C@@H](C(N)=O)CC1=CC=C(O)C=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	RDP-58 (acetate)
Available
Product Description	Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide acetate inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide acetate can be used for the research of ulcerative colitis[1][2].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	1288.62
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	IFNAR; Reactive Oxygen Species; TNF Receptor
Manufacturers Target	IFNAR; Reactive Oxygen Species; TNF Receptor
Manufacturers Pathway	Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Peptides

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